Oxidative stress—the imbalance between free radicals and antioxidants in the body—plays a crucial role in tissue damage and repair. Wellbeing International Foundation has conducted pioneering research into how addressing this factor can significantly enhance healing and recovery.
When cells burn oxygen during normal metabolism or intense exercise, they produce reactive oxygen species (ROS) that can damage cellular components. This oxidative damage is particularly pronounced in highly active tissues like muscles and can significantly impair recovery following injury or intense physical exertion.
The foundation’s research has revealed that extracellular vesicles (EVs) derived from mesenchymal stem cells contain a powerful antioxidant protein called superoxide dismutase (SOD2). This enzyme plays a vital role in neutralising harmful free radicals, protecting cells from oxidative damage, and creating an environment conducive to repair.
For athletes, this antioxidant protection has significant implications. As documented in research by Dr. Stephen Ray, skeletal muscle is one of the most metabolically active tissues in the human body. During intense exercise, muscles accumulate oxidative damage that can limit performance and extend recovery times. By enhancing the body’s natural antioxidant defences, Wellbeing’s treatment helps maintain muscle function and accelerate post-exercise recovery.
The benefits extend beyond muscular health. Research indicates that SOD2 also protects motor nerves—essential for muscle contraction and coordination—from oxidative damage. This neurological protection represents another dimension of the foundation’s comprehensive approach to tissue health.
Published studies in collaboration with academic institutions have demonstrated that EV treatment significantly reduces markers of oxidative stress in damaged tissues. This research, appearing in respected scientific journals, validates the foundation’s approach and contributes valuable knowledge to the field of regenerative medicine.
By addressing oxidative stress as part of their therapeutic strategy, Wellbeing International Foundation is tackling a fundamental aspect of cellular damage and ageing. Their innovative approach represents a significant advancement in our understanding of tissue repair and offers new possibilities for promoting recovery and maintaining optimal health in both athletic and clinical contexts.